This paper discusses the usage of Optimized Pulse Pattern (OPP) modulation to increase the efficiency of the inverter and the permanent magnet synchronous motor (PMSM) by reducing switching losses in the inverter together with copper and iron losses in the electric motor. It presents a unique implementation of Optimized Pulse Patterns dynamically selected upon speed/torque operating setpoints using several optimization criteria and performed by an FPCU integrated circuit. The efficiency improvement is measured on a high-voltage bench and compared to conventional SVPWM modulation, both using a comparable field-oriented control (FOC) of the drive. As a result, using OPP, loss reductions are in the range of 2% to 4.6% regarding motor and inverter have been achieved.